From Richard Nordquist,
Your Guide to Grammar & Composition.
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The narrator of Jonathan Lethem's novel Motherless Brooklyn (1999) is Lionel Essrog, an orphan with Tourette syndrome. In the novel's opening paragraph, which follows, Essrog describes his neurological disorder through metaphors and extended personification.

from Motherless Brooklyn

by Jonathan Lethem

Context is everything. Dress me up and see. I'm a carnival barker, an auctioneer, a downtown performance artist, a speaker in tongues, a senator drunk on filibuster. I've got Tourette's. My mouth won't quit, though mostly I whisper or subvocalize like I'm reading aloud, my Adam's apple bobbing, jaw muscle beating like a miniature heart under my cheek, the noise suppressed, the words escaping silently, mere ghosts of themselves, husks empty of breath and tone. (If I were a Dick Tracy villain, I'd have to be Mumbles.) In this diminished form the words rush out of the cornucopia of my brain to course over the surface of the world, tickling reality like fingers on piano keys. Caressing, nudging. They're an invisible army on a peacekeeping mission, a peaceable horde. They mean no harm. They placate, interpret, massage. Everywhere they're smoothing down imperfections, putting hairs in place, putting ducks in a row, replacing divots. Counting and polishing the silver. Patting old ladies gently on the behind, eliciting a giggle. Only--here's the rub--when they find too much perfection, when the surface is already buffed smooth, the ducks already orderly, the old ladies complacent, then my little army rebels, breaks into the stores. Reality needs a prick here and there, the carpet needs a flaw. My words begin plucking at threads nervously, seeking purchase, a weak point, a vulnerable ear. That's when it comes, the urge to shout in the church, the nursery, the crowded movie house. It's an itch at first. Inconsequential. But that itch is soon a torrent behind a straining dam. Noah's flood. That itch is my whole life. Here it comes now. Cover your ears. Build an ark.

"Eat me!" I scream.

Selected Works by Jonathan Lethem:

• As She Climbed Across the Table, a novel (1997)
• Motherless Brooklyn, a novel (1999)
• The Fortress of Solitude, a novel (2003)
• The Disappointment Artist, essays (2005)

Motherless Brooklyn, by Jonathan Lethem, was published by Doubleday in 1999.