As both a noun and an adjective, prostate refers to a male gland. As an adjective, prostrate means lying flat on the ground or reduced to extreme weakness. The verb prostrate means to put oneself into a submissive position.
Examples:
Practice:
(a) As both players lay _____, the referee reached for a red penalty card.
(b) Cancers, even specific ones like breast and _____, vary in their behavior.

